U.S. patent application 20200033045 (applicant Packaging Technology Group Inc., Fall River, Mass.):
"A temperature-controlled product shipper includes a phase change material bladder which can be filled at the point of packaging. The shipper includes an internal product box and an outer box where the product box is received within the outer box. The phase change material bladder is received within a cavity defined between the outer surface of the product box and the inner surface of the outer box. The shipper may also include an insulated liner which is received between the product box and the bladder."